RADIATION

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Reactive Cellular Changes Associated with Radiation

"Cell size is markedly increased without a substantial increase in the nuclear to cytoplasmic ratio.

Bizarre cell shapes may occur.

Nuclei may vary in size, with some cell groups having both enlarged and normal-sized nuclei.

Binucleation or multinucleation is common. Mild nuclear hyperchromasia may be present.

Enlarged nuclei may show degenerative changes including nuclear pallor, wrinkling or smudging of the chromatin, and nuclear vacuolization."

— Nayar, R. & Wilbur, D.C. (Eds.). The Bethesda System for Reporting Cervical Cytology: Definitions, Criteria, and Explanatory Notes. 3rd ed. Springer, 2015

This website is not affiliated with or endorsed by the authors, editors, or publishers of The Bethesda System for Reporting Cervical Cytology. Content quoted is used strictly for educational and informational purposes.

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